How do you decide when to cash out your position?

I’m in my late-20s, and one of the stocks I own shot up 30% this week. I’m now up approximately 230% and could cash out the position for about $22,000. My original goal was $15,000. I like the company but I feel like it’s going to be very volatile from this point forward (pending-FDA Approval) and I think it’s time to lock in my profit with big life events on the horizon (wedding and buying a house). I’ve owned the stock for 2 years it was one of my first investments. Keep in mind, I’m asking h

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